Products
Ofloxacin solution for infusion
Pharmacotherapeutic group
Antimicrobial drug, fluoroquinoloneInternational name
OfloxacinDosage form
Solution for infusionThe bactericidal effect of ofloxacin is due to its inhibition of DNA gyrase resulting in blocking of bacterial DNA replication and microbial cell death. Ofloxacin has a broad spectrum of antimicrobial activity, particularly, against microorganisms resistant to other antibiotics, including beta-lactamase producing strains. It is active against such Gram-positive microorganisms as Staphylococcus aureus (methicillin-susceptible strains) and Staphylococcus epidermidis as well as against most of Gram-negative aerobes: Aeromonas hydrophila, Citrobacter koseri, Сhlamydia trachomatis, Chlamydia pneumoniae, Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, beta-lactamase producing and non-producing strains of Haemophilus influenzae, Haemophilis parainfluenzae, Klebsiella pneumoniae, Klebsiella oxytoca, Legionella pneumophila, beta-lactamase producing and non-producing strains of Neisseria gonorrhoeae, Neisseria meningitidis, Proteus mirabilis, Proteus vulgaris, Plesiomonas spp., Salmonella enterica, Shigella spp., Serratia marcescens, Yersinia enterocolitica.