Products
Interfast®
Pharmacotherapeutic group
Antiviral for the treatment of HIV infections, protease inhibitorInternational name
SaquinavirDosage form
TabletsAntiretroviral drug, HIV protease inhibitor.
HIV protease is the key viral enzyme essential for specific cleavage of Gal and Gag-Pol structural polypeptides of the virus. These viral polypeptides have a cleavage site recognized only by HIV protease and other closely related viral proteases.
Saquinavir, a peptide-like structural analogue of these cleavage sites, is a selective and reversible HIV protease inhibitor and it prevents formation of mature viral particles.