Products
Anastrozole
Pharmacotherapeutic group
Antitumor hormonal drugs and hormone antagonists; aromatase inhibitorsInternational name
AnastrozoleDosage form
TabletsAntineoplastic drug. It is a selective nonsteroidal aromatase inhibitor. In postmenopausal women, estradiol is produced primarily from estrone which is converted from androstenedione to through the aromatase enzyme in peripheral tissues. Reducing circulating estradiol levels produces a beneficial effect in women with breast cancer. In postmenopausal women, anastrozole at a daily dose of 1 mg produces estradiol suppression by 80%. Anastrozole does not possess any progestogenic, androgenic, or estrogenic activity and does not have any effect on cortisol or aldosterone secretion when taken at therapeutic doses.