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The bactericidal effect of ofloxacin is due to its inhibition of DNA gyrase resulting in blocking of bacterial DNA replication and microbial cell death. Ofloxacin has a broad spectrum of antimicrobial activity, particularly, against microorganisms resistant to other antibiotics, including beta-lactamase producing strains. It is active against such Gram-positive microorganisms as Staphylococcus aureus (methicillin-susceptible strains) and Staphylococcus epidermidis as well as against most of Gram-negative aerobes: Aeromonas hydrophila, Citrobacter koseri, Сhlamydia trachomatis, Chlamydia pneumoniae, Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, beta-lactamase producing and non-producing strains of Haemophilus influenzae, Haemophilis parainfluenzae, Klebsiella pneumoniae, Klebsiella oxytoca, Legionella pneumophila, beta-lactamase producing and non-producing strains of Neisseria gonorrhoeae, Neisseria meningitidis, Proteus mirabilis, Proteus vulgaris, Plesiomonas spp., Salmonella enterica, Shigella spp., Serratia marcescens, Yersinia enterocolitica.

Manufacturer

LLC EAST-PHARM

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