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Products

Remdeform
Pharmacotherapeutic group
Antiviral drug
International name
Remdesivir
Dosage form
Lyophilized for solution for infusion
Description Manufacturer Pharmacies Leave a feedback
Antiviral agent. Remdesivir is an adenosine nucleotide pro-drug that is metabolized within host cells to form nucleoside triphosphate, its pharmacologically active metabolite. Remdesivir triphosphate acts as an analog of adenosine triphosphate (ATP) and competes with the natural ATP substrate for incorporation into nascent RNA chains by the SARS-CoV-2 RNA-dependent RNA polymerase, which results in delayed chain termination during replication of the viral RNA. No clinical data are available on the development of SARS-CoV-2 resistance to remdesivir. Drug products containing remdesivir were registered under the emergency registration procedure for drug products intended for use in a threat of emergency, actual emergency and emergency management. The patient information leaflets are based on limited clinical data on the drug product use and will be updated as soon as new data become available. Drug products containing remdesivir are authorized for use in inpatient care settings only.
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