Products

Gemcivin

Pharmacotherapeutic group

Antineoplastic drug, antimetabolite

International name

Gemcitabine

Dosage form

Lyophilized for concentrate for solution for infusion

Product information

Download Gemcivin.pdf (RU)
Go to the State Register of Medicinal Products site ➞

Description Manufacturer Pharmacies Leave a feedback

Antineoplastic drug. Gemcitabine has a cytostatic effect associated with inhibition of DNA synthesis. It undergoes intracellular metabolism to form active diphosphate and triphosphate nucleosides. Diphosphate nucleoside inhibits ribonucleotide reductase, an enzyme involved in the synthesis of deoxynucleoside triphosphates required for DNA synthesis, which results in reducing their intracellular levels. Triphosphate nucleoside actively competes for incorporation into DNA and it can also incorporate into RNA. Following incorporation of gemcitabine intracellular metabolites into DNA, one additional nucleotide is added to the growing DNA strand, which leads to complete inhibition of further DNA synthesis and apoptotic cell death.

Send

NAME AND SURNAME*

E-mail

Subject*

Message*

Captcha*

* — Required field

Данный сайт содержит информацию о лекарственных препаратах, отпускаемых по рецепту.

В соответствии со статьей 67 Федерального закона от 12.04.2010 № 61-ФЗ «Об обращении лекарственных средств» материалы данного сайта предназначены (и могут быть доступны) исключительно для медицинских и фармацевтических работников. АО «Фармасинтез» не несет ответственность за возможные негативные последствия, возникшие в результате использования информации данного сайта без предварительной консультации со специалистом лицами, не являющимися медицинскими и фармацевтическими работниками.

Choose who you are:

Patient

Healthcare professional

Distributor

Products

LEAVE A FEEDBACK

We care about the consumers health and our medicines.