Scientific expertise

Pharmasyntez-Nord

The Pharmasyntez-Nord R&D centre develops biological medicines through the full cycle. Projects progress from genetic construct design and the generation of a producer cell line to the development of manufacturing technology, a finished dosage form and quality control methods.

The centre works with monoclonal antibodies, insulins, recombinant and Fc-fusion proteins, enzymes, viral vectors, vaccines and ADCs. Its specialists develop cultivation and purification processes, investigate biosimilarity, demonstrate the biological activity and viral safety of medicines, and transfer technologies to manufacturing sites.

More than 250 R&D specialists, over 2,000 m² of laboratories and more than 25 projects in active development. Work follows GLP and GMP standards, with quality control throughout the medicine’s life cycle.

BratskChemSyntez

The BratskChemSyntez research centre develops technologies for manufacturing existing pharmaceutical ingredients and synthesising innovative small molecules.

The centre combines advanced equipment with expertise across the full cycle. Staff have access to modern reactor systems, spectrometers and scanning probe microscopes. Highly qualified chemists provide analytical support using state-of-the-art instrumental methods. The most complex tasks are addressed by a laboratory for advanced research methods, equipped with the latest generation of mass spectrometers. The centre also has laboratories for the development of oligonucleotides and anticancer pharmaceutical ingredients, with isolator protection.

A key advantage of the centre is its own pilot production unit, with reactors of up to 250 L, enabling independent scale-up. Over 5 years, a team of 50 people developed and transferred more than 40 technologies into production. Synthesis involved an average of 3 chemical steps, with a maximum of 11.

Pharmasyntez-Tyumen

Undertakes comprehensive pharmaceutical development of generic medicines, from selecting a formulation concept and manufacturing technology to launching industrial production.

The centre’s work includes analytical support for development and demonstration of bioequivalence. At each stage, specialists assess the medicine’s characteristics and prepare the data needed for the transition to industrial production.

Pharmasyntez-Medtech

The design department develops medical equipment: specialists in engineering design, software and circuit design work together on product structures, electronic assemblies and control algorithms. A separate team designs polymer consumables for dialysis and prepares the design documentation needed to bring them into production.